CRO/CMC/CDMOCDMO capability profile

CDMO 2

An integrated discovery-to-commercialization provider spanning research reagents, custom synthesis, process development, analytical and quality control, CMC, APIs, drug product and commercial manufacturing.

Core modalities

small moleculeADC/XDCpeptideoligonucleotidebiologicdrug product

Pre-generated AI ranking

Potential U.S. biotech customers

Score model: gpt-5.4-miniGenerated: Aug 24, 2026, 7:24 PM PDTRead-only snapshot

1
Wave Life Sciences
Cambridge, Massachusettspublic clinical-stage biotech
95match score

Wave has a diversified RNA pipeline and multiple chemistry modalities that fit CDMO 2 oligonucleotide and analytical capabilities.

Recommended services

oligonucleotide process developmentconjugationanalytical and CMC

Public evidence

Official site lists RNA editing, RNAi, splicing and antisense clinical programs. Source

2
Arrowhead Pharmaceuticals
Pasadena, Californiapublic commercial-stage biotech
94match score

Arrowhead has a large RNAi pipeline and marketed product, creating strong technical fit but potentially entrenched late-stage suppliers.

Recommended services

oligonucleotide process developmentanalytical methodscommercial supply

Public evidence

Official pipeline includes marketed and Phase 3 RNAi medicines. Source

3
Dyne Therapeutics
Waltham, Massachusettspublic late-clinical-stage biotech
92match score

Dyne has late-stage oligonucleotide conjugates and follow-on programs that align with CDMO 2 process, analytical and manufacturing services.

Recommended services

oligonucleotide CDMOconjugationlate-stage CMC

Public evidence

Official pipeline includes regulatory-stage and Phase 3 conjugated oligonucleotide programs. Source

4
PepGen
Boston, Massachusettspublic clinical-stage biotech
91match score

PepGen peptide-oligonucleotide conjugates directly overlap with CDMO 2 peptide, oligonucleotide and conjugation capabilities.

Recommended services

peptide process developmentoligonucleotide process developmentconjugation

Public evidence

Official pipeline centers on a Phase 2 peptide-conjugated oligonucleotide. Source

5
Sutro Biopharma
South San Francisco, Californiapublic clinical-stage biotech
90match score

Sutro next-generation ADC programs align with CDMO 2 ADC, linker, payload, conjugation and manufacturing services.

Recommended services

ADC linker and payloadbioconjugationhigh-potency manufacturing

Public evidence

Official pipeline lists multiple single- and dual-payload ADC programs. Source

6
Nurix Therapeutics
San Francisco, Californiapublic clinical-stage biotech
89match score

Nurix combines targeted degraders with degrader-antibody conjugates, matching CDMO 2 complex chemistry and conjugation capabilities.

Recommended services

degrader chemistryADC conjugationhigh-potency API

Public evidence

Official pipeline identifies degrader and conjugate programs across clinical stages. Source

7
IDEAYA Biosciences
South San Francisco, Californiapublic clinical-stage biotech
88match score

IDEAYA operates both small-molecule and ADC pipelines across several clinical stages, matching CDMO 2 breadth from discovery through manufacturing.

Recommended services

small-molecule CDMOADC linker and payloadhigh-potency APICMC

Public evidence

Official pipeline shows nine clinical-stage programs across small molecules and ADCs. Source

8
Immunome
Bothell, Washingtonpublic clinical-stage biotech
87match score

Immunome has one clinical and multiple preclinical ADC programs, creating clear demand categories for ADC development and manufacturing support.

Recommended services

ADC CDMOlinker and payloadhigh-potency API

Public evidence

Official pipeline lists clinical and preclinical ADC candidates. Source

9
Revolution Medicines
Redwood City, Californiapublic late-clinical-stage biotech
83match score

Revolution Medicines has complex clinical RAS inhibitors with technical fit for process and manufacturing services, but likely established suppliers.

Recommended services

small-molecule CDMOAPI scale-upcommercial CMC

Public evidence

Official pipeline lists multiple late- and early-clinical oral RAS inhibitors. Source

10
Kura Oncology
San Diego, California and Boston, Massachusettspublic commercial-stage biotech
82match score

Kura has relevant small-molecule manufacturing needs, though its commercial stage suggests a higher switching barrier.

Recommended services

API manufacturinganalytical and CMCcommercial supply

Public evidence

Official pipeline includes an approved small molecule and several clinical programs. Source

11
Kymera Therapeutics
Watertown, Massachusettspublic clinical-stage biotech
81match score

Kymera targeted degraders align with CDMO 2 complex small-molecule and CMC capabilities.

Recommended services

degrader chemistryprocess developmentAPI and CMC

Public evidence

Official site describes a multi-program clinical degrader pipeline. Source

12
Monte Rosa Therapeutics
Boston, Massachusettspublic clinical-stage biotech
80match score

Monte Rosa molecular glue degraders require complex small-molecule synthesis and CMC support that fit CDMO 2 capabilities.

Recommended services

small-molecule CDMOdegrader chemistryCMC

Public evidence

Official pipeline lists clinical and preclinical molecular glue degraders. Source

13
Treeline Biosciences
Watertown, Massachusettsprivate clinical-stage biotech
79match score

Treeline spans inhibitors, degraders and ADCs, closely matching CDMO 2 broad discovery and CDMO platform.

Recommended services

small-molecule CDMOdegrader chemistryADC CDMO

Public evidence

Official site describes clinical small-molecule/degrader programs and an ADC capability. Source

14
Relay Therapeutics
Cambridge, Massachusettspublic clinical-stage biotech
77match score

Relay precision small molecules fit CDMO 2 discovery chemistry, custom synthesis and process capabilities.

Recommended services

small-molecule CROcustom synthesisprocess development

Public evidence

Official pipeline lists clinical and early-stage precision small molecules. Source

15
Septerna
South San Francisco, Californiapublic clinical-stage biotech
76match score

Septerna is moving several oral small-molecule programs toward and through clinical development, fitting integrated CRO/CDMO support.

Recommended services

small-molecule CROprocess developmentCMC

Public evidence

Official pipeline lists discovery, IND-enabling and Phase 1 GPCR programs. Source

16
Frontier Medicines
Boston, Massachusetts and South San Francisco, Californiaprivate clinical-stage biotech
75match score

Frontier has multiple covalent small-molecule programs whose discovery and scale-up needs match CDMO 2 services.

Recommended services

small-molecule CROprocess developmentAPI manufacturing

Public evidence

Official site describes a clinical and preclinical covalent small-molecule pipeline. Source

17
Nimbus Therapeutics
Boston, Massachusettsprivate clinical-stage biotech
74match score

Nimbus has a renewable clinical and preclinical small-molecule portfolio fitting CDMO 2 chemistry and development services.

Recommended services

custom synthesisprocess developmentAPI and CMC

Public evidence

Official pipeline covers small molecules in oncology, immunology and metabolism. Source

18
Odyssey Therapeutics
Boston, Massachusettspublic clinical-stage biotech
72match score

Odyssey has a growing set of small-molecule immunology assets across early and clinical stages.

Recommended services

small-molecule CROcustom synthesisprocess development

Public evidence

Official pipeline lists multiple small-molecule programs from discovery to Phase 2. Source

19
Arvinas
New Haven, Connecticutpublic commercial-stage biotech
68match score

Arvinas programs fit CDMO 2 degrader and manufacturing capabilities, although commercialization maturity may lower near-term vendor openness.

Recommended services

degrader chemistryAPI manufacturingcommercial CMC

Public evidence

Official pipeline includes approved and clinical PROTAC programs. Source

20
Neumora Therapeutics
Watertown, Massachusettspublic clinical-stage biotech
60match score

Neumora has several small-molecule assets at transition points where integrated chemistry and CMC support may add capacity.

Recommended services

small-molecule CROIND-enabling CMCAPI manufacturing

Public evidence

Official pipeline lists preclinical through Phase 2 small molecules. Source